Standard Protocol (2 mL = 5 mg/mL)
| Phase | Example amount (mcg) | Units (per measurement) (mL) |
|---|---|---|
| Days 1–20 (Cycle On) | 5,000 mcg (5 mg) | 100 units (1.00 mL) |
| Weeks 4–26 (Cycle Off) | 0 mcg | — |
Frequency: Measure once daily, preferably in the evening or at bedtime to synergize with natural melatonin rhythms[3]. Complete 20 consecutive days, then observe a 4–6 month off-cycle before repeating (typically 2 cycles per year)[5].
Reconstitution Steps
- Draw 2.0 mL bacteriostatic water with a sterile syringe.
- Measure slowly down the vial wall; avoid foaming.
- Gently swirl/roll until dissolved (do not shake).
- Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Important: This guide is for educational purposes only and is not medical advice. For research use only. Not for human consumption.
How This Works
Epitalon’s primary mechanism involves telomerase activation, promoting telomere elongation in cells[2]. In vitro studies demonstrated that Epitalon induced telomerase and lengthened telomeres in human cell cultures, allowing cells to continue dividing beyond the usual Hayflick limit[9]. Epitalon also influences the neuroendocrine system by stimulating nocturnal melatonin release from the pineal gland, thereby normalizing circadian hormone rhythms in aged subjects[3]. Additional reported effects include antioxidant activity, genomic regulatory effects, and immune modulation[1].