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Research Reference

Adipotide Research Reference

Complete research reference and reconstitution guide for Adipotide.

Research Use Only Reconstitution Math Storage Reference

Quick Reference

Vial Amount
10mg
CoreVials Standard Mix
Add 1mL BAC Water
Final Concentration
10mg/mL
Easy Reference
10 units = 1mg
Storage
Refrigerate after reconstitution

This page is for research-use-only educational reference and measurement math. It is not medical, veterinary, dosing, administration, or treatment guidance. Products are not for human or animal consumption.

On this page

How This Works

Adipotide is a peptidomimetic compound designed to selectively target blood vessels within white adipose tissue by binding to prohibitin‑1 on the vascular endothelium[2][8]. Once bound, it delivers a pro‑apoptotic sequence that triggers vessel destruction, cutting off the blood supply to fat cells and causing them to undergo apoptosis and be metabolized[1][2]. Preclinical studies in obese rodents demonstrated approximately 30% body weight reduction, and obese primates showed about 11% weight loss after 4 weeks of research model[1][9]. A first‑in‑human Phase 1 trial was initiated in obese cancer research samples[3], but further clinical development was discontinued due to strategic and safety reasons, including reversible renal effects observed at higher doses[4].

CoreVials Standard Mix

For a 10mg vial Add 1mL BAC Water
Final concentration 10mg/mL

After mixing (U-100 syringe reference)

  • 5 units=0.5mg
  • 10 units=1mg
  • 20 units=2mg

These are example measurement calculations only. They are not dosing, administration, medical, or veterinary guidance.

Other Mix Options
BAC Added Final Concentration 0.5mg Equals 1mg Equals
1mL CoreVials Standard Mix 10mg/mL 5 units 10 units
2mL 5mg/mL 10 units 20 units
3mL 3.33mg/mL 15 units 30 units

Supply Planning

Products commonly paired for research preparation:

  • Adipotide Research Reference
  • BAC Water
  • Cryo labels
  • Storage case
Shop Peptides View BAC Water

References

Science Translational Medicine (PubMed)
— A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys

MD Anderson Cancer Center
— Obese Monkeys Lose Weight on Drug that Attacks Blood Supply of Fat Cells

Arrowhead Pharmaceuticals News
— Measurement of First Research sample with Anti-Obesity Research model Adipotide in a Phase 1 Clinical Trial

Cardiovascular Diabetology (PMC)
— Advances and challenges of targeting epicardial adipose tissue (EAT) and perivascular adipose tissue (PVAT)

Bachem Technical Note
— Care and Handling of Peptides

BC Open Textbook Project
— 7.3 Intradermal and Measurements – Clinical Procedures for Safer Research sample Care

Immunize.org (IAC)
— Ask the Experts: Preparing Vaccines – General Issues (no aspiration guidance)

Los Angeles Times
— Cancer research model shows promise for rapid weight loss

ScienceDaily
— Obese monkeys lose weight on drug that attacks blood supply of fat cells

CDC
— Vaccine preparation: route guidance

CDC (Subcut Measurement PDF)
— Technique diagram and site guidance for measurements

NCBI Bookshelf
— Best practices for measurement (asepsis, preparation, and preparation)

Drug Measurement Review (PMC)
— Pharmacologic considerations of the route

Research Use Notice

This page is research-use-only educational reference and measurement math. It is not medical, veterinary, dosing, administration, or treatment guidance. Products are not for human or animal consumption.

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High-purity peptides and lab essentials with batch-level COA transparency.

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Related Protocols

Research Use Only Products are for laboratory research only, not for human or animal consumption. Research Compliance