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Research Reference

CJC-1295 No DAC Research Reference

Complete research reference and reconstitution guide for CJC-1295 No DAC.

Research Use Only Reconstitution Math Storage Reference

Quick Reference

Vial Amount
5mg
CoreVials Standard Mix
Add 10 mL BAC Water
Final Concentration
0.5 mg/mL
Easy Reference
10 units = 50 mcg
Storage
Refrigerate after reconstitution
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This page is for research-use-only educational reference and measurement math. It is not medical, veterinary, dosing, administration, or treatment guidance. Products are not for human or animal consumption.

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How This Works

CJC-1295 NO DAC (Modified GRF 1–29) is a truncated GHRH analog with four amino acid substitutions (D‑Ala2, Gln8, Ala15, Leu27) that enhance stability against enzymatic degradation[1]. It binds to GHRH receptors on pituitary somatotrophs, stimulating the synthesis and pulsatile release of endogenous growth hormone[2][3]. Unlike exogenous GH preparation, GHRH analogs preserve the physiologic feedback loop, resulting in more natural GH pulsatility without the risks associated with supraphysiological GH levels[7]. The short half‑life (~30 minutes) produces discrete GH pulses that mimic the body’s natural secretion pattern[1][4].

CoreVials Standard Mix

For a 5mg vial Add 10 mL BAC Water
Final concentration 0.5 mg/mL

After mixing (U-100 syringe reference)

  • 5 units=25 mcg
  • 10 units=50 mcg
  • 20 units=100 mcg

These are example measurement calculations only. They are not dosing, administration, medical, or veterinary guidance.

Other Mix Options
BAC Added Final Concentration Dose per 10 units
10 mL CoreVials Standard Mix 0.5 mg/mL 50 mcg
10 mL 1 mg/mL 100 mcg

Supply Planning

Products commonly paired for research preparation:

  • CJC-1295 (No DAC)
  • BAC Water
  • Cryo labels
  • Storage case

References

Wikipedia
— Modified GRF (1–29): structure, amino acid substitutions, and pharmacokinetics

Journal of Clinical Endocrinology & Metabolism (2006)
— Teichman et al.: Prolonged stimulation of GH and IGF‑I by CJC-1295 in healthy adults

American Journal of Physiology (2006)
— Alba et al.: Once‑daily CJC-1295 normalizes growth in GHRH knockout mice

Journal of Clinical Endocrinology & Metabolism (2006)
— Veldhuis et al.: Pulsatile GH secretion persists during continuous CJC-1295 stimulation

PMC
— Growth Hormone Secretagogue Research model in Hypogonadal Men Raises Serum IGF‑1 Levels

PMC
— Effects of GHRH Analog (Tesamorelin) on Endogenous GH Pulsatility and Insulin Sensitivity

PMC
— Sermorelin: a better approach to management of adult‑onset growth hormone insufficiency

PMC
— Beyond the androgen receptor: role of GHS in body composition in hypogonadal males

PMC
— The Safety and Efficacy of Growth Hormone Secretagogues (Review)

PMC
— GHRH Effects on Brain GABA Levels in Mild Cognitive Impairment and Healthy Aging

PubMed
— Sermorelin: review of its use in diagnosis and research model of GH deficiency

CDC
— Vaccine preparation: route (angle/site; no aspiration)

CDC (Subcut Measurement PDF)
— Technique diagram and site guidance for measurements

NCBI Bookshelf
— Best practices for measurement (asepsis, preparation, and preparation)

Drug Measurement Review (PMC)
— Pharmacologic considerations of the route

Research Use Notice

This page is research-use-only educational reference and measurement math. It is not medical, veterinary, dosing, administration, or treatment guidance. Products are not for human or animal consumption.

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