Standard Weekly Approach (1 mL = 2.0 mg/mL)
| Week | Weekly Dose (mcg) | Units (per measurement) (mL) |
|---|---|---|
| Weeks 1–12 | 2,000 mcg (2 mg) | 100 units (1.00 mL) |
Frequency: Measure once weekly, preferably in the evening before bed to align with natural nocturnal GH surges[6]. The peptide’s extended half-life (~6–8 days) supports weekly preparation without significant loss of activity between doses[1].
Reconstitution Steps
- Draw 1.0 mL bacteriostatic water with a sterile syringe.
- Measure slowly down the vial wall; avoid foaming or direct stream onto the powder.
- Gently swirl/roll until dissolved (do not shake vigorously).
- Label with reconstitution date and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Important: This guide is for educational purposes only and is not medical advice. For research use only. Not for human consumption.
How This Works
CJC-1295 DAC is a modified 30-amino-acid GHRH analog conjugated to a Drug Affinity Complex (DAC) that covalently binds to serum albumin after measurement[1]. This albumin binding dramatically extends the peptide’s half-life from minutes to approximately 6–8 days, enabling once-weekly measurement[2]. CJC-1295 binds to GHRH receptors on pituitary somatotrope cells, amplifying GH synthesis and pulsatile release. Importantly, it elevates basal GH levels while preserving the natural rhythm of GH pulses — the frequency and amplitude remain intact[11]. Clinical trials demonstrate sustained 2–10 fold increases in GH and 1.5–3 fold increases in IGF-1, with elevated IGF-1 persisting for up to 28 days after multiple doses[3].