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Research Reference

Neuroxelin Research Reference

Complete research reference and reconstitution guide for Neuroxelin.

Research Use Only Reconstitution Math Storage Reference

Quick Reference

Vial Amount
48mg
CoreVials Standard Mix
Add 1mL BAC Water
Final Concentration
48mg/mL
Easy Reference
10 units = 4.8mg
Storage
Refrigerate after reconstitution

This page is for research-use-only educational reference and measurement math. It is not medical, veterinary, dosing, administration, or treatment guidance. Products are not for human or animal consumption.

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How This Works

Neuroxelin is designed to intervene in the cascade of brain injury through multiple mechanisms. It may dampen excitotoxic neuron death by disrupting NMDA receptor signaling pathways, similar to nerinetide (NA-1), which interferes with PSD-95 protein interactions[1]. Additionally, Neuroxelin-class peptides can reduce neuroinflammation by downregulating microglial activation and cytokine release, as demonstrated in studies of apoE-mimetic peptides like CN-105[2]. The peptide may also provide neurotrophic support by promoting synaptic repair and neurogenesis, supporting neuronal survival and vascular repair following acute brain injuries[3][7].

CoreVials Standard Mix

For a 48mg vial Add 1mL BAC Water
Final concentration 48mg/mL

After mixing (U-100 syringe reference)

  • 5 units=2.4mg
  • 10 units=4.8mg
  • 20 units=9.6mg

These are example measurement calculations only. They are not dosing, administration, medical, or veterinary guidance.

Other Mix Options
BAC Added Final Concentration 0.5mg Equals 1mg Equals
1mL CoreVials Standard Mix 48mg/mL 1.04 units 2.08 units
2mL 24mg/mL 2.08 units 4.17 units
3mL 16mg/mL 3.13 units 6.25 units

Supply Planning

Products commonly paired for research preparation:

  • Neuroxelin Research Reference
  • BAC Water
  • Cryo labels
  • Storage case
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References

The Lancet
— Efficacy and safety of nerinetide for acute ischaemic stroke (ESCAPE-NA1): Phase 3 RCT of PSD-95 inhibitor peptide

Scientific Reports (Nature)
— Neuroprotective pentapeptide CN-105 reduces sterile inflammation and improves outcomes in TBI murine model

Drugs (Springer/PubMed)
— Efficacy and safety of sovateltide in acute cerebral ischaemic stroke: Phase III clinical trial

Nutrients (PMC)
— Neuropsychological performance after extended N-Pep-12 supplementation in ischemic stroke (12-month study)

GenScript
— Peptide storage and handling guidelines: stability, reconstitution, and freeze-thaw considerations

NIBSC (UK MHRA)
— Peptide handling, dissolution, and storage guidelines from standards agency

Biochimica et Biophysica Acta (ScienceDirect)
— Advances in clinical studies of peptide drugs in stroke disease: mechanisms and progress

Stroke (AHA Journals)
— Factors influencing nerinetide effect on infarct volume in stroke research samples

PubMed
— Phase 1 randomized, double-blind, placebo-controlled study of CN-105 safety and pharmacokinetics

CDC
— Vaccine preparation: handling reference (angle, site, no aspiration)

CDC
— Vaccine preparation during vaccination: measurement guidance

Advances in Research (PMC)
— measurement of drugs: factors influencing pain sensation at preparation area

Translational Psychiatry (Nature)
— Davunetide effects on memory in prodromal Alzheimer’s disease

Schizophrenia Research (ScienceDirect)
— Effect of the neuroprotective peptide davunetide (AL-108) on cognition and safety

Research Use Notice

This page is research-use-only educational reference and measurement math. It is not medical, veterinary, dosing, administration, or treatment guidance. Products are not for human or animal consumption.

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Related Protocols

Research Use Only Products are for laboratory research only, not for human or animal consumption. Research Compliance