CJC-1295 DAC (5 mg Vial) —, Once Weekly
Reconstitution: 2.0 mL bacteriostatic water → 2.5 mg/mL (2500 mcg/mL) → 25 mcg per unit
| Phase | Weekly Dose (mcg / mg) | Units (mL) per Measurement | Frequency |
|---|---|---|---|
| Standard | 1000 mcg (1.0 mg) | 40 units (0.40 mL) | Once weekly |
| Aggressive | 2000 mcg (2.0 mg) | 80 units (0.80 mL) | Once weekly |
Note: At 2.5 mg/mL, each 5 mg vial provides 2.5 standard doses (1 mg each) or 1.25 aggressive doses (2 mg each).
CJC-1295 DAC Reconstitution Steps
- Draw 2.0 mL bacteriostatic water with a sterile syringe.
- Measure slowly down the vial wall; avoid foaming or direct stream onto powder.
- Gently swirl/roll until fully dissolved (do not shake).
- Label with date and refrigerate at 2–8 °C (35.6–46.4 °F).
Ipamorelin (5 mg Vial) —, Once Daily
Reconstitution: 3.0 mL bacteriostatic water → 1.67 mg/mL (1666.7 mcg/mL) → 16.67 mcg per unit
| Phase | Example amount (mcg / mg) | Units (mL) per Measurement | Frequency |
|---|---|---|---|
| Weeks 1–2 (Initiation) | 100 mcg (0.1 mg) | 6 units (0.06 mL) | Once daily |
| Weeks 3–4 (Titration) | 150 mcg (0.15 mg) | 9 units (0.09 mL) | Once daily |
| Weeks 5+ (Maintenance) | 200 mcg (0.2 mg) | 12 units (0.12 mL) | Once daily |
| Aggressive (Optional) | 300 mcg (0.3 mg) | 18 units (0.18 mL) | Once daily or split 2×/day |
For ≤10-unit (≤0.10 mL) administrations, consider 30- or 50-unit insulin syringes for improved readability.
Ipamorelin Reconstitution Steps
- Draw 3.0 mL bacteriostatic water with a sterile syringe.
- Measure slowly down the vial wall; avoid foaming.
- Gently swirl/roll until dissolved (do not shake).
- Label with date and refrigerate at 2–8 °C (35.6–46.4 °F).
How This Works
CJC-1295 DAC functions as a synthetic GHRH analog that stimulates pituitary GH release. Its Drug Affinity Complex (DAC) moiety binds to serum albumin, extending its half-life to approximately 6–8 days and producing sustained, dose-dependent elevations in GH and IGF-1[1]. Ipamorelin is a selective growth hormone secretagogue that activates the ghrelin receptor (GHSR) to trigger rapid GH pulses without significantly affecting ACTH, cortisol, or prolactin[2]. When combined, these peptides act through complementary pathways—GHRH receptor and ghrelin receptor—to synergistically amplify endogenous GH secretion[3].